Ever watched Two A Days? Popular reality TV show about 11-12 years ago that focused on Hoover HS in Hoover, Alabama outside of Birmingham. They were a monster team, Hoover. In 2005 they played against Allen D. Nease HS from Ponte Vedra Beach, FL, which is outside of Jacksonville I do believe. Their quarterback that season was Tim Tebow, who was in his senior year at Nease. Nease came to Hoover. Nease had a 7.5 hour drive to Hoover. Hoover won 50-29.
The game was played on a Saturday.
It is feasible and it would take some planning.